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Vol. 15 Núm. 2 (2024)
Vol. 15 Núm. 2 (2024): Vol 15, Núm.2 (2024): Julio-Diciembre

Artículos de investigación / Research papers

Efecto de Lactobacillus lactis microencapsulado sobre Klebsiella pneumoniae bajo condiciones gastrointestinales in-vitro

https://doi.org/10.19053/uptc.01217488.v15.n2.2024.17201

Publicado 2024-07-23

  • Henry Jurado-Gámez
    • ,
  • Jhon Fredy Ceron Cordoba

Henry Jurado-Gámez
University of Nariño image/svg+xml

Jhon Fredy Ceron Cordoba
Investigador

Resumen

K. pneumoniae se encuentra de forma nativa en los tractos respiratorio y gastrointestinal de humanos, animales domésticos y salvajes con posibles vínculos zoonóticos. está comúnmente asociada con infecciones nosocomiales y se ha reportado en algunos alimentos como vector de transmisión. Los Lactobacillus se consideran una alternativa preventiva para al uso de antibióticos en salud animal y humana, gracias a la producción de ácido láctico, ácidos orgánicos, exopolisacáridos (EPS) y metabolitos secundarios con propiedades antibacterianas, antioxidantes, reológicas y conservación de alimentos. El objetivo de la investigación es evaluar el potencial inhibitorio de Lactobacillus lactis microencapsulado mediante secado por aspersión sobre Klebsiella pneumoniae bajo condiciones gastrointestinales in-vitro. Se realizan pruebas como producción de gas, actividad de catalasa, crecimiento a diferente temperatura, cinética de fermentación, microencapsulación de la cepa láctica, estudio estructural del material microencapsulado, supervivencia en condiciones gastrointestinales in-vitro y pruebas de inhibición de L. lactis sobre K. pneumoniae. Los resultados indican efecto protector del microencapsulado sobre L. lactis, respuesta inhibitoria de la cepa láctica sobre K. pneumoniae.

Palabras clave

Klebsiella pneumoniae, Lactobacillus, microencapsulación, salud humana, salud animal, zoonosis

PDF

Citas

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