Autistic spectrum disorders: clinical characterization in children and adolescents from a reference center in Tunja, Boyacá.

Abstract
Introduction: DSM V defines Autism Spectrum Disorders (ASD) as deficiencies in communication and social interaction, through repetitive behavior patterns. The etiology is multifactorial, involving genetic and environmental factors. Early detection is crucial, but lacks of data in Boyacá distinguish the need for local research to c interventions. Objective: make clinical characterization of the population of children and adolescents diagnosed with ASD attending to a reference center in Tunja, Boyacá. Methodology: We carried out a retrospective observational study on children and adolescents diagnosed as ASD in Boyacá. Cases older than 18 years and registered prior to 2021 were excluded. Clinical records from 2021 to 2023 were reviewed, collecting demographic data, family history, and developmental aspects. Information was gathered using a Google Forms questionnaire and analyzed using frequency and central tendency measures. Results: Data were obtained from 214 patients, which 20 were diagnosed with autism spectrum disorders, with an age of diagnosis between 3-6 years. The most frequent autism spectrum disorder was moderate (75%), with the most common symptom being late language development (100%) followed by impaired connection with the environment (80%). Conclusions: It would be pertinent to carry out a collaborative departmental study in the future that allows including the different institutions that provide child care services in Boyacá to obtain a more significant sample and more precise results.
Keywords
Rett Syndrome, Autism spectrum disorder, Prevalence, Biotypology
Author Biography
Jessica del Pilar Castellanos Hernández
Medical Student Pedagogical and Technological University of Colombia
Diego Mauricio Enríquez Erazo
Medical Student Pedagogical and Technological University of Colombia
María José Erazo Muñoz
Medical Student Pedagogical and Technological University of Colombia
Duane Dexter Mitchell Hawkins
Medical Student Pedagogical and Technological University of Colombia
References
- Artigas-Pallares J, Paula I. El autismo 70 años después. Leo Kanner y Hans Asperger [Internet]. Asociación Española de Neuropsiquiatría; [cited 2023 Dec 18]. Available from: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S021157352012000300008#:~:text=Y%20lleg%C3%B3%20Leo%20Kanner.,affective%20contact%22%20(11)
- Asperger H. Die ‘‘Autistischen Psychopathen’’ im Kindesalter. Archiv für Psychiatrie und Nervenkrankheiten. 1944; 117(1): 76-136.
- Asociación Americana de Psiquiatría, Guía de consulta de los criterios diagnósticos del DSM V Arlington, VA, Asociación Americana de Psiquiatría, 2013. Disponible en:
- https://www.eafit.edu.co/ninos/reddelaspreguntas/Documents/dsm-v-guia-consultamanual-diagnostico-estadistico-trastornos-mentales.pdf
- Sanchack KE, Thomas CA. Autism spectrum disorder: Primary care principles [Internet].
- [cited 2023 Dec 11]. Available from: https://www.aafp.org/pubs/afp/issues/2016/1215/p972.html
- Chaste P, Leboyer M. Autism risk factors: genes, environment, and gene-environment interactions. Dialogues Clin Neurosci [Internet]. 2012 [citado el 11 de diciembre de
- ; 14(3):281–92. Disponible en: http://dx.doi.org/10.31887/dcns.2012.14.3/pchaste
- Al-Dewik NI. Risk factors diagnosis prognosis and treatment of autism. Front Biosci
- [Internet].2020; 25(9):1682–717. Disponible en: http://dx.doi.org/10.2741/4873
- Gardener H, Spiegelman D, Buka SL. Perinatal and neonatal risk factors for autism: A comprehensive meta-analysis. Pediatrics [Internet]. 2011 [citado el 19 de diciembre de
- ; 128(2):344–55. Disponible en: http://dx.doi.org/10.1542/peds.2010-1036
- Maenner MJ, Shaw KA, Baio J, Washington A, Patrick M, DiRienzo M, et al. Prevalence
- of Autism Spectrum Disorder Among Children Aged 8 Years - Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2016. MMWR Surveill Summ.
- ; 69 (4):1-12.
- Zeidan J, Fombonne E, Scorah J, Ibrahim A, Durkin MS, Saxena S, Yusuf A, Shih A,
- Elsabbagh M. Global prevalence of autism: A systematic review update. Autism Res. 2022
- May;15(5):778-790. doi: 10.1002/aur.2696. Epub 2022 Mar 3. PMID: 35238171; PMCID:
- PMC9310578. https://pubmed.ncbi.nlm.nih.gov/35238171/
- Ivan David De La Peña Sanabria, Giovanetti LB, Ruiz NC, Diana Carolina López Gulfo,
- Manjarez LMR, Charria ODS, et al. Caracterización de Niños y adolescentes con Trastornos del Espectro Autista en Barranquilla, Colombia [Internet]. [cited 2023 Dec 12]. Available from:
- https://revistapediatria.org/rp/article/view/244#:~:text=La%20prevalencia%20viene%20en%20ascenso,la%20liga%20colombiana%20de%20autismo.
- Oduardo-Pérez A, Rodríguez-Puga R, Llanes-Oduardo E, Gómez-Cardoso Á,
- Núñez-Rodríguez O, Cortiñas-Noy A. Caracterización clínico-epidemiológica de pacientes pediátricos con diagnóstico de trastorno del espectro autista. Revista del Hospital Psiquiátrico de La Habana [Internet]. 2023 [citado 12 Dic 2023]; 20 (2) Disponible en:
- https://revhph.sld.cu/index.php/hph/article/view/311
- Larsson HJ, Eaton WW, Madsen KM, Vestergaard M, Olesen AV, Agerbo E, et al. Risk factors for autism: Perinatal factors, parental psychiatric history, and socioeconomic status. Am J Epidemiol [Internet].2005;161(10):916–25. Disponible en: http://dx.doi.org/10.1093/aje/kwi123
- Beversdorf DQ, Stevens HE, Jones KL. Prenatal stress, maternal immune dysregulation, and their association with autism spectrum disorders. Curr Psychiatry Rep [Internet]. 2018 [citado el 19 de diciembre de 2023]; 20(9):76. Disponible en:
- http://dx.doi.org/10.1007/s11920-018-0945-4
- Walder DJ, Laplante DP, Sousa-Pires A, Veru F, Brunet A, King S. Prenatal maternal stress predicts autism traits in 6½ year-old children: Project Ice Storm. Psychiatry Res [Internet].2014 [citado el 19 de diciembre de 2023]; 219(2):353–60. Disponible en: https://pubmed.ncbi.nlm.nih.gov/24907222/
- C. Talero-Gutiérrez. Caracterización de Niños y adolescentes con Trastornos del Espectro Autista en una Institución de Bogotá, Colombia [Internet]. Elsevier Doyma; 2011 [cited 2023 Dec 16]. Available from:
- https://www.sciencedirect.com/science/article/pii/S0213485311001393
- López Valencia AK, Bastida Mercado E. Caracterización clínica de pacientes con trastorno del espectro autista en la consulta externa de neurología pediátrica. Archivos de Investigación Materno Infantil [Internet]. 2022; 13(2):67–78. Disponible en: https://www.medigraphic.com/pdfs/imi/imi-2022/imi222c.pdf
- Eugenia Espinosa, Paola Mera, Daniel Toledo. Trastorno del espectro autista: caracterización clínica en pacientes de dos centros de referencia en Bogotá, Colombia [internet]. 2017 [cited 2023 dec 18]. Available from:
- https://revistas.unimilitar.edu.co/index.php/rmed/article/view/3990/3307